Sleep and Menopause

Hot flashes are depicted as a sensation of heat, sweating, flashing, anxiety, and chills lasting one to five minutes and are reported by up to 84% of women in natural menopause. A hot flash is a heat-dissipation response, consisting of peripheral vasodilation, and sweating beginning in the upper part of the body. We believe that in the absence of estrogen, the hypo-thalamus becomes more sensitive to core body temperature changes over a much narrower temperature range.

Research on Sleep and Menopause

Perimenopausal women were recruited from the San Francisco Bay area community over a four-year period. Women included here were participating in an ongo-ing study about sleep quality during the menopausal transition Thirty-four women (Age, mean±SD: 50.4±2.7 years; BMI, mean±SD: 24.3±3.6 kg.m; 23 white) met inclusion criteria and were included in the analysis.

Upon awakening in the morning, women completed sleep and hot flash questionnaires. They reported the number of perceived awakenings (Awakenings), wake after sleep onset (WASO, min), and sleep quality on a 100 mm visual analogue scale, ranging from 0, “very bad”, to 100, “very good” (SQ), as used elsewhere. They also were asked to report the number of nocturnal hot flashes experienced (HF-number) and how bothered they were by hot flashes/night sweats during the night (HF-bother), as used elsewhere.

Take Home Message on Menopause and Sleep

The authors found that hot-flash associated wake time accounted for, on average, 27.2% of PSG-defined wakefulness during the night in peri-menopausal women.aging and sleep

In another study published in the Journal of Endocrinology and Metabolism when women were awake long enough to recall nighttime hot flashes, that perception contributed to mood disturbances and anxiety.

I believe the take home message here is that we need to screen our peri-menopausal and post-menopausal patients who present with moodiness and anxiety for sleep disturbances. The incidence of insomnia as well as sleep apnea increases remarkably during the menopause.

Sleep Medications for Menopause

There are many available options for hot flashes. Effective therapies include low dose estrogen, gabapentin, SSRI and SSNRIs such as paroxetine and other sleeping pills like venlafaxine and Lunesta (eszopiclone) which in a recent study was found to be effective in menopausal hot flashes. In fact, a simple behavioral technique of lowering the thermostat works for some. Another alternative to pharmaceutical treatment is the Embr wrist band.  This novel approach applies sensation to the wrist, activating natural reaction through pathways to the brain, providing instant relief to hot flashes.

Summarized by: Robert S. Rosenberg, DO, FCCP, is the medical director of the Sleep Disorders Center of Prescott Valley, Arizona and sleep medicine consultant for Mountain Heart Health Services in Flagstaff, Arizona. Dr. Rosenberg is Board Certified in Sleep Medicine, Pulmonary Medicine, and Internal Medicine. His book Sleep Soundly Every Night, Feel Fantastic Every Day  is a best seller. Dr Rosenberg’s latest book is The Doctor’s Guide to Sleep Solutions for Stress & Anxiety. Visit Dr Rosenberg’s website which offers a wealth of information on sleep topics.

Magnitude of the Impact of Hot Flashes on Sleep in Perimenopausal Women
Massimiliano de Zambotti, PhD, Ian M. Colrain, PhD, Harold S. Javitz, PhD, and Fiona C. Baker, PhD
Fertility and Sterility Volume 102 Issue 6

2 thoughts on “Sleep and Menopause

  1. Marketa Kropacova Reply

    I’ve had friends experience different symptoms during the menopause. One suffered a lot from insomnia and anxiety while another friend of mine hardly suffered from any symptoms at all. Apparently her mother didn’t have much of an issue either so family genes and symptoms being hereditary must play a part here on some level.

  2. M Murphy Reply

    At 74, I have experienced menopausal night sweats EVERY 1 1/2 – 2 1/2 hrs. EVERY night for the past 30 years. With an abundance of breast/uterine cancer in my family, I am considered high risk for the use of HRT. I have tried thousands of dollars of over the counter recommendations for relief including bio-identicals. My Mother died at 92 yrs. of age, still experiencing daily hot flashes and night sweats, I have one living sister, age 87….still experiencing hot flashes although not as severely as I do. I am a short sleeper (as defined at this website), I am not a sleep apnea candidate, according to your questionnaire, but am overweight, which started accumulating when I became post menopausal at 52. What do you recommend for improving the quality of my sleep?

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